Edmonton's Cosmetic Surgery Clinic
Question:
My skin frequently feels dry,
especially after showers. When I go to the store, I am confused with all the
moisturizer choices. How do I choose a good moisturizer for my skin?
Answer:
Moisturizers –
Are they really needed? The truth is that moisturizers are a growing component
of daily skin care and account for one of the most common over the counter
products sold in North America. This growth is
partly due to the fact that what started as a simple moisturizer has become a
sophisticated vehicle for delivery of complex nourishment and regulatory
molecules to the skin. The following article introduces the reader to the basic
structure of moisturizer as well its potential use for elegant delivery of
therapeutic compounds.
The moisturizers are mostly used for one of the
following reasons:
1 – To repair the skin’s
ability to provide an effective barrier against outside pollutants, toxins,
bacteria, viruses, fungi and to prevent the essential components of our skin
and tissues from escaping our bodies.
2 – To increase the
water content of the skin in both dermis [deeper layer of the skin] and
epidermis
[outermost layer of the skin].
3 – To reduce skin
vulnerability against trans-epidermal (through the skin) water loss.
4 – To rebalance the
skin’s composition of lipids (fats) both inside and outside the skin cells.
5 – To deliver nutrients
and regulatory substances to the viable portion of the dermis and epidermis.

The anatomy of
most moisturizers encompasses at least one of the following components:
emollients, occlusive agents, humectants as well as additives designed to add
extra benefits to the traditional functions of the moisturizers.
Emollients,
such as fatty acids, dimethicone or isopropyl palmitate, improve the visual
aspect of the skin by sealing the tiny splits between the components of stratum
corneum (outmost, non-living part of the epidermis). These properties account
for the resulting skin softness and smoothness when emollients are used in a
moisturizer.
Occlusive
agents such as petrolatum, lanolin, mineral oil or silicones, block
trans-epidermal water loss. Petrolatum is the most potent occlusive agents and,
as such, can be used extensively in patients with compromised skin barrier (in
patients with atopic dermatitis [eczema]). Even at low concentrations, such as
5% petroleum jelly, it can reduce water loss through the skin by 98%. Because
of the powerful occlusive properties, these agents have to be used carefully on
the face as acne cosmetica [acne related to the use of cosmetics] can result.
Humectants
such as glycerin, propylene glycol and urea, are designed to attract water
either from the environment or from the underlying dermis to the epidermis.
Since humectants can also draw water from the dermis, they can actually
increase the trans-epidermal water loss. The water that is moved from the
dermis to the epidermis can evaporate from the skin’s surface paradoxically
resulting in dry skin. It is for this reason that most humectants are used in
combination with an occlusive agent. This accomplishes two functions: moisture
retention and prevention of water loss.
The era of
newer, much more sophisticated moisturizers is upon us where scientifically
formulated delivery systems can offer additive benefits of supplementing and
modulating skin cells for their optimal function and differentiation. As such,
these new moisturizers offer a cutting edge frontier where therapeutic benefits
are combined with the moisturizing qualities of topical products. Vitamins,
minerals, growth factors, peptides, enzymes and co-enzymes are some of the few
categories of molecules currently in use in the latest fight to prevent skin
deterioration and optimize its functioning.
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